whereas, if clinical studies may be accepted, it is taken as given that such studies comply with the Helsinki Declaration and OECD Guidelines for Good Clinical Practice;

Appropriate elements of OECD guideline 417 are to be used.

This requires the introduction of a new set of tests based on EN ISO standards and OECD guidelines, which governs the granting of direct permission for placing detergents on the market.

The test must be carried out in accordance with OECD Guideline 418.

The 'shake flask` method described is based on the OECD Test Guideline (1).

OECD, Paris, 1981, Test Guideline 102, Decision of the Council C(81) 30 final.

OECD, Paris, 1981, Test Guideline 201, Decision of the Council C(81) 30 Final.

OECD, Paris, 1981, Test Guideline 203, Decision of the Council C(81) 30 final and updates.

OECD, Paris, 1981, Test Guidelines 202, Decision of the Council C(81) 30 final and updates.

"culture of network and information security" has the same meaning as that set out in the OECD Guidelines for the security of Information Systems and Networks of 25 July 2002 and the Council Resolution of 18 February 2003 on a European approach towards a culture of network and information security(17).

To evaluate medium- and long-term effects after acute, sub-acute or semi-chronic exposure to micro-organisms, it is necessary to use the options provided in most of the OECD guidelines, to extend the studies concerned with a recovery period (after which full macroscopic and microscopic pathology is to be performed, including an exploration for micro-organisms in the tissues and organs).

Thus, before biological testing according to the present test guideline is considered, a UV/vis absorption spectrum of the test chemical should be determined (e.g. according to OECD Test Guideline 101).

The Community is party to the OECD Arrangement on guidelines for officially supported export credits, hereinafter referred to as "the Arrangement";

In the case of liquid preparations for Ultra Low Volume use (ULV) the kinematic viscosity must be determined and reported according to OECD Test Guideline 114.

The Community is a party to the Arrangement on guidelines for officially supported export credits concluded within the OECD, hereinafter referred to as "the Arrangement".

Where dissociation in water occurs, the dissociation constant(s) (pKa values) of the purified active substance must be determined and reported according to OECD Test Guideline 112.

The inspection guidelines recommended by the United Nations Economic Commission for Europe, themselves in line with the relevant OECD recommendations, should be adopted to this end.

The Community is party to the Arrangement on guidelines for officially supported export credits (hereinafter referred to as the "Arrangement") concluded within the framework of the OECD;

Most of these methods are developed within the framework of the OECD programme for Testing Guidelines, and should be performed in conformity with the principles of Good Laboratory Practice, in order to ensure as wide as possible "mutual acceptance of data".

In the absence of any scientifically validated alternative methods to animal experiments and any pertinent toxicity test guidelines in the field of alternative methods adopted by the OECD, it was necessary to postpone the date provided for in Article 4(1)(i) of Directive 76/768/EEC for the first time by Commission Directive 97/18/EC in compliance with the second subparagraph of this provision.

The second subparagraph of this provision also provides that the Commission should submit draft measures to postpone the date of implementation of this provision if there has been insufficient progress in developing satisfactory methods to replace animal testing, and in particular in those cases where alternative methods of testing, despite all reasonable endeavours, have not been scientifically validated as offering an equivalent level of protection for the consumer, taking into account OECD toxicity test guidelines.

If there has been insufficient progress in developing satisfactory methods to replace animal testing, and in particular in those cases where alternative methods of testing, despite all reasonable endeavours, have not been scientifically validated as offering an equivalent level of protection for the consumer, taking into account OECD toxicity test guidelines, the Commission shall, by 1 January 1997, submit draft measures to postpone the date of implementation of this provision, for a sufficient period, and in any case for no less than two years, in accordance with the procedure laid down in Article 10.