A series of methods such as high performance liquid chromatography (HPLC) with fluorimetric detection, liquid chromatography (LC)-mass spectrometry (MS), inmunoassays and functional assays such as the phosphatase inhibition assay can be used as alternative or complementary methods to the biological testing methods, provided that either alone or combined they can detect at least the following analogues, that they are not less effective than the biological methods and that their implementation provides an equivalent level of public health protection:
Kot alternativne ali komplementarne metode biološkim poskusnim metodam se lahko uporabi vrsta metod, kot je tekočinska kromatografija velike zmogljivosti (HPLC) s fluorimetričnim zaznavanjem, tekočinska kromatografija (LC), masna spektrometrija (MS), imunske metode in funkcionalni poskusi, kot je poskus zaviranja encima fosfataze, če je mogoče zaznati najmanj naslednje analoge s posameznimi metodami, ali s kombinacijo metod, ki niso manj učinkovite od bioloških metod in če njihova uporaba zagotavlja enakovredno raven varovanja javnega zdravja: