Masna spektrometrična detekcija se izvaja z uporabo MS tehnik, kot so snemanje celotnih masnih spektrov (full scan) ali izbrano spremljanje ionov (SIM), kakor tudi tehnike MS-MSn kot je izbrano spremljanje reakcije (SMR) ali druge primerne MS ali MS-MSn tehnike v kombinaciji z ustreznimi načini ionizacije.
Mass-spectrometric detection shall be carried out by employing MS-techniques such as recording of full mass spectra (full scans) or selected ion monitoring (SIM), as well as MS-MSn techniques such as Selected Reaction Monitoring (SRM), or other suitable MS or MS-MSn techniques in combination with appropriate ionisation modes.