A collaborative trial has been organised to provide the evidence that the level of 10,0 μg/kg can be reliably determined.

A maximum level of 10,0 μg/kg has been established for apple juice and solid apple products, including apple compote and apple puree, for infants and young children and other baby food on the condition that a method of analysis would have been validated by an international collaborative ring trial to be performed before 1 November 2003 in order to demonstrate that the level of 10 μg/kg patulin can be reliably determined.

Year of interlaboratory test

Statistical results of the interlaboratory test

Statistical results of the interlaboratory test:

organise interlaboratory aptitude tests,

The results from the collaborative trial shall be published or freely available.

The necessary collaborative trials and studies should be planned and conducted in accordance with international guidelines.

Interlaboratory study (comparison) means organisation, performance and evaluation of tests on the same sample by two or more laboratories in accordance with predetermined conditions to determine testing performance.

The precision values referred to in 1 (iii) shall be obtained from a collaborative trial which has been conducted in accordance with an internationally recognized protocol on collaborative trials (e. g. International Organization of Standarization 'Precision of Test Methods' (ISO 57257 1981)).

The ISO 8692 - Water quality - Fresh water algal growth inhibition test with Scenedesmus subspicatus and Selenastrum capricornutum reports the following results for an inter-laboratory test among 16 laboratories, testing potassium dichromate:

material validated by an interlaboratory test,

1997 Proficiency testing by interlaboratory comparisons - Part 1:

Details of the interlaboratory trial on the accuracy of the method are summarised in Appendix B.

However, for some of the procedure, collaborative trials have not been carried out.

Results from internationally accepted collaborative trials are not yet available.

Results from internationally accepted collaborative trials are not available.

require the use of proficiency testing schemes as far as appropriate.

Figures for repeatability (r) and reproducibility (R) from international collaborative trials are not available.

They are calculated from the results of recognized collaborative trials which have been used to evaluate the procedure.

A collaborative trial has been organised to provide the evidence that the level of 10,0 μg/kg can be reliably determined.

The collaborative trials and studies referred to in 5.1.3 should be planned and conducted in accordance with international guidelines.

The values derived from the interlaboratory trial may not be applicable to ranges of analyte concentration and matrices other than those in Appendix B.

Whereas the preferred SBI configuration has been subject to an inter-laboratory ('round robin`) testing programme covering a wide range of construction materials;

Where possible, the validation shall include a certified reference material in the collaborative trial test materials.

This competence should be documented by a successful participation in collaborative studies, proficiency tests or interlaboratory comparisons.

Where possible, the validation shall include a certified reference material in the collaborative trial test materials. A specific method has been validated by collaborative trial and has been shown to meet the requirements of Table 4 (c).

The method has been tested in an intercomparison made at international level in 1990 using four different feedingstuffs (mixed pig feed, broiler compound, protein concentrate, premixture).

According to the Annex to Directive 85/591/EEC the precision values for methods of analysis which are to be considered for adoption under the provisions of that Directive shall be obtained from a collaborative trial which has preferably been conducted in accordance with ISO 5725-1986.

Until such time as the reproducibility of a method has been established by a collaborative trial, then for the purpose of preselection of candidate methods by desk review, it is necessary that data on repeatability, recovery and results obtained for certified reference materials are available.

Member States shall ensure that laboratories carrying out official controls on the presence of animal constituents in feedingstuffs participate periodically in proficiency testing on the analytical methods, and that laboratory personnel carrying out analyses receive adequate training.

Besides the positive control chemical chlorpromazine which should be concurrently tested in each assay, for newly establishing the 3T3 NRU phototoxicity test it is recommended to use as reference chemicals a subset from the chemicals used in interlaboratory trials with the present test (1) (3) (13).

The ISO 8692 - Water quality - Fresh water algal growth inhibition test with Scenedesmus subspicatus andSelenastrum capricornutum reports the following results for an inter-laboratory test among 16 laboratories, testing potassium dichromate :

A maximum level of 10,0 μg/kg has been established for apple juice and solid apple products, including apple compote and apple puree, for infants and young children and other baby food on the condition that a method of analysis would have been validated by an international collaborative ring trial to be performed before 1 November 2003 in order to demonstrate that the level of 10 μg/kg patulin can be reliably determined.