Če neki mednarodni standard, smernica ali priporočilo ne obstaja ali pa vsebina predlaganega sanitarnega ali fitosanitarnega predpisa v pretežni meri ni enaka mednarodnemu standardu, smernici ali priporočilu, lahko pa pomembno vpliva na trgovino drugih članic, članice:
Whenever an international standard, guideline or recommendation does not exist or the content of a proposed sanitary or phytosanitary regulation is not substantially the same as the content of an international standard, guideline or recommendation, and if the regulation may have a significant effect on trade of other Members, Members shall: