Za vsako preskušano kemikalijo se celice enako zasejejo v dve ločeni 96-kanalni plošči, ki gresta nato hkrati čez celotni preskusni postopek pod enakimi pogoji kultiviranja, razen časovnega obdobja, v katerem se ena plošča obseva (+ UVA/vidna svetloba), druga pa ostane v temi (- UVA/vidna svetloba).
For each test chemical, cells are seeded identically in two separate 96-well plates, which are then taken concurrently through the whole test procedure under identical culture conditions, except for the time period where one of the plates is irradiated (+ UVA/vis) and the other one is kept in the dark (- UVA/vis).