Neuspeh, da bi zmanjšali breme teh bolezni, in njihov dokazano naraščajoč vpliv so jih postavili v središče razvojnih razprav - kot dokazujeta Deklaracija zavez, sprejeta na posebnem zasedanju Generalne skupščine ZN junija 2001, ki priznava, da HIV/AIDS predstavlja izredno stanje, ki grozi razvoju, in razglasitev tuberkuloze in malarije za globalno izredno stisko na zasedanju Svetovne zdravstvene skupščine WHO - in vodili k zahtevam po nujnih ukrepih in vrsti nacionalnih, regionalnih in mednarodnih pobud, namenjenih doseganju Razvojnih ciljev tisočletja, ki zajemajo jasne cilje za boj proti HIV/AIDSU, tuberkulozi in malariji, k izpolnjevanju katerih se je zavezala Evropska skupnost in njene države članice.
The failure to reduce the burden of these diseases and the evidence of their increasing impact have brought them to the centre of the development debate - as evidenced by the Declaration of Commitment of the Special Session of the UN General Assembly of June 2001, which recognises that HIV/AIDS has evolved to become a developmental emergency, and by the WHO World Health Assembly's declaration of tuberculosis and malaria as global emergencies - and have led to calls for urgent action and a series of national, regional and international initiatives, all meant to achieve the Millennium Development Goals which include clear targets to fight HIV/AIDS, tuberculosis and malaria, and to which the European Community and its Member States committed themselves.